EPA Releases Alternative Approaches to Skin Sensitization

April 12, 2018

EPA published this week its draft document, “Interim Science Policy: Use of Alternative Approaches for Skin Sensitization as a Replacement for Laboratory Animal Testing.”

The document outlines alternative approaches to determine whether chemicals cause an allergic reaction, inflammation, or sensitization of the skin, and it details the Agency’s science behind the use of the alternative approach methods for in vitro, in silico, and in chemico testing.

“This draft policy is another step toward achieving EPA's goal of reducing the use of animals and increasing the use of cutting-edge science in chemical testing,” said EPA Administrator Scott Pruitt.

EPA notes it will begin accepting testing submissions immediately that are in accordance with the methodologies outlined in the draft document.

Comments on the draft document must be submitted by June 9.